A 56-year-old physician attends your office the day after an upper endoscopy performed for dyspeptic symptoms. He has already read the report, which mentions diffusely thickened gastric folds. He is very worried and asks about the potential differential diagnosis.



Which of the following is not a differential diagnosis for thickened gastric folds?

A 79-year-old man is evaluated for epigastric pain, loss of appetite, and early satiety. Upper endoscopy reveals a submucosal mass in the gastric antrum. EUS shows a 4 × 6 cm mass in the mid stomach arising from the second layer (mucosa/lamina propria).



On the basis of the endosonographic appearance, which tumor is most likely?

A 56-year-old man attends for review of his Barrett's esophagus (BE). He was diagnosed 8 years ago with short-segment non dysplastic Barrett's esophagus, (NDBE), which was confirmed 12 months later. He had endoscopies 5 and 2 years ago, which continued to show NDBE.



He asks, of 1000 patients in my scenario, how many develop esophageal adenocarcinoma (EAC) each year?

A 27-year-old woman with idiopathic gastroparesis diagnosed 6 months ago is hospitalized with dehydration from persistent nausea and vomiting. She is now unable to keep down solid foods and has limited tolerance of liquids. She has lost 20 lb in the past month (baseline weight 132 lb, height 5′ 6″). Prior endoscopy with gastric biopsy was normal. An upper GI barium study showed delayed gastric transit with normal duodenal transit and no obstruction. Her recent abdominal X-ray is normal.



What method should be used to provide nutrition support?

A 60-year-old man who has Prague classification C6M8 Barrett's esophagus and a single nodule that is removed with endoscopic mucosal resection is found to have high-grade dysplasia. The remainder of the esophagus is non-dysplastic. RFA of his remaining Barrett's esophagus is recommended. Following complete ablation, which takes three RFA treatments, he appears to have complete remission from intestinal metaplasia.



After 5 years, what is the approximate likelihood of recurrent Barrett's esophagus in this patient?